Hokkaido University Hospital,
N-15, W-7, Kita-ku, Sapporo, Hokkaido 060-8638
Japan
Research Article
The Prevalence of Cerebral Microbleeds in HIV-Infected Hemophilia Patients
Author(s): Tomoyuki Endo, Hideki Goto, Naohiro Miyashita, Takahide Ara, Kohei Kasahara, Kohei Okada, Soichi Shiratori, Junichi Sugita, Masahiro Onozawa, Daigo Hashimoto, Masao Nakagawa, Kaoru Kahata, Katsuya Fujimoto, Takeshi Kondo, Satoshi Hashino, Kiyohiro Houkin, Kiyohiro Houkin and Takanori TeshimaTomoyuki Endo, Hideki Goto, Naohiro Miyashita, Takahide Ara, Kohei Kasahara, Kohei Okada, Soichi Shiratori, Junichi Sugita, Masahiro Onozawa, Daigo Hashimoto, Masao Nakagawa, Kaoru Kahata, Katsuya Fujimoto, Takeshi Kondo, Satoshi Hashino, Kiyohiro Houkin, Kiyohiro Houkin and Takanori Teshima
Objective: Several studies have shown that rates of cerebrovascular events in HIV-infected patients are increased in comparison to uninfected individuals. In addition, cerebral bleeding represents a serious complication in hemophilia patients. Recently, asymptomatic cerebral microbleeds (CMBs), which can be detected by highly sensitive techniques such as T2*-weighted magnetic resonance imaging (MRI), have emerged as an important marker for predicting symptomatic cerebral bleeding. The aim of the present study was to investigate the prevalence of CMBs in HIVinfected hemophilia patients and to evaluate the association between HIV infection and cerebral bleeding. Methods: All HIV-infected hemophilia patients (HIV+ HemPts) who visited our hospital from January 2015 to December 2016 were enrolled in this study. In addition, all HIV-uninfected hemophi.. Read More»
DOI:
10.4172/2155-6113.1000747
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report