Molecular Biomarkers & Diagnosis

Toshi Jain

Publications

• Research Article
  PowerPlex Y23 System: A Fast, Sensitive and Reliable Y-STR Multiplex System for Forensic and Population Genetic Purpose
  Author(s): Toshi Jain, Pankaj Shrivastava, Bansal DD, Dash HR and Veena Ben TrivediToshi Jain, Pankaj Shrivastava, Bansal DD, Dash HR and Veena Ben Trivedi
  
  Y-STR genotyping is an excellent tool for the identification of male DNA masked by female DNA, particularly in sexual assault cases where, more often the male and female components cannot be separated completely. Resultant, the female component could exist prominently even in the male component after separation. When the "male DNA sample mixed with female DNA” undergoes PCR by using autosomal STR multiplex amplification process, the female DNA component is also amplified, mostly masking the male DNA. Recently launched Y-STR kit, PowerPlex Y23 (PP Y23) System is a 5-dye multiplex genotyping kit that analyzes 17 Y-STR loci, commonly available in other Y-STR multiplex kits (DYS19, DYS385a/b, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and Y-GATA-H4) along with that 6 new Y-STR loci (DYS481, DYS533,.. Read More»
  DOI: 10.4172/2155-9929.1000281

  Abstract PDF