Spain
Research Article
Transient Elastography for Predicting Liver-Related Events in Cirrhotic
HIV-Infected Patients
Author(s): Montes ML, Berenguer J, Miró JM, Quereda C, Hernando A, Sanz J, Ortega E, Tural C, Wichmann MA, Zamora FX and Gónzalez-García JJMontes ML, Berenguer J, Miró JM, Quereda C, Hernando A, Sanz J, Ortega E, Tural C, Wichmann MA, Zamora FX and Gónzalez-García JJ
Aim: We assessed liver stiffness measurement (LSM) for the prediction of mortality and decompensation in HIVinfected patients with compensated liver cirrhosis. Method: A prospective cohort study of HIV-infected patients with confirmed liver cirrhosis from 9 hospitals in Spain. LSM was undertaken for each patient; clinical events were collected prospectively after the baseline visit, and patients were followed until death or the censoring date. We used univariate/multivariate Cox proportional hazard models to evaluate the utility of LSM for predicting the first hepatic decompensation or overall mortality. The sensitivity (SEN), specificity (SPE), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+) and negative likelihood ratio (LR-) were calculated. The LSM cutoff was selected using ROC curves. Results: We included 102 patients with compe.. Read More»
DOI:
10.4172/2155-6113.1000675
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report