Pharmaceutical Regulatory Affairs: Open Access

Uehara C

Publications

• Research Article
  Screening of Compounds from an FDA-Approved Drug Library for the Ability to Inhibit Aspartic Protease Secretion from the Pathogenic Yeast Candida albicans
  Author(s): Cho O, Shiokama T, Ando Y, Aoki N, Uehara C, Maeda E, Matsumoto S, Kurakado S and Sugita TCho O, Shiokama T, Ando Y, Aoki N, Uehara C, Maeda E, Matsumoto S, Kurakado S and Sugita T
  
  The pathogenic fungus Candida albicans causes disseminated candidiasis with a poor prognosis in immunocompromised hosts. Secreted aspartyl protease (Sap) from the microorganism acts as a hydrolase to facilitate invasion into host tissues. Inhibition of Candida Sap activity could b.. Read More»
  DOI: 10.4172/2167-7689.1000126

  Abstract PDF