Hospital Universitario Virgen Macarena,
Spain
Case Report
Myxofibrosarcoma Following Chemotherapy and Radiotherapy for
Hodgkin's Lymphoma: Case Study and Review
Author(s): Vallejo-Benítez Ana, Rodríguez-Zarco Enrique, Pabón-Carrasco Sara, Pereira-Gallardo Sofía, Villar-Rodríguez Jose Luis and González-Cámpora RicardoVallejo-Benítez Ana, Rodríguez-Zarco Enrique, Pabón-Carrasco Sara, Pereira-Gallardo Sofía, Villar-Rodríguez Jose Luis and González-Cámpora Ricardo
Introduction: Although radiation-induced sarcomas are widely documented, most reports focus on pleomorphic malignant fibrous histiocytomas (high-grade undifferentiated pleomorphic sarcomas); few case studies involve myxofibrosarcomas. This paper reports on a grade II myxofibrosarcoma of the neck arising secondary to earlier chemotherapy and radiotherapy. Material and methods: A 61-year-old male received chemotherapy plus radiotherapy in 1983 for nodular sclerosing Hodgkin's lymphoma. Twenty-six years after completing treatment, the patient developed a grade II myxofibrosarcoma involving radiated soft tissue on the left side of the neck. Results: The tumor was removed. The tumor mass weighed 90 g and measured 6 × 5 × 4.5 cm and the histological examination revealed a grade-II superficial malignant myxoid spindle-cell tumor displaying a multinodular growth pattern. Immunohis.. Read More»
DOI:
10.4172/2165-7920.1000816
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report