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Review Article
Comparison of Efficacy and Safety Outcomes in Randomized Trials of
Long-Acting and Short-Acting ?2-Agonists for Chronic Obstructive
Pulmonary Disease: A Review
Author(s): Vamsi K Bollu, John Karafilidis, Ann Colosia, Lee Bennett and Nicola HananiaVamsi K Bollu, John Karafilidis, Ann Colosia, Lee Bennett and Nicola Hanania
Limited information is available comparing the efficacy and safety of Short-Acting β2-agonists (SABAs) versus long-acting β2-agonists (LABAs) for maintenance therapy in Chronic Obstructive Pulmonary Disease (COPD). The objective of this research was to conduct a systematic literature review and evaluate COPD-related outcomes in a meta-analysis. The literature review identified randomized clinical trials of LABAs and SABAs as maintenance therapy in adults with stable COPD. PubMed/Medline, Embase, and the Cochrane Library were searched for reports published between January 1, 1990 and July 16, 2010. Only studies of at least 2 weeks in duration were included. Few studies directly comparing LABAs and SABAs were expected; therefore, studies with placebo or .. Read More»
DOI:
10.4172/2161-105X.1000137
Pulmonary & Respiratory Medicine received 1690 citations as per Google Scholar report