Journal of Nephrology & Therapeutics

Vangelis Manolopoulos

Publications

• Research Article
  Adiponectin Plasma Levels and Albuminuria in Patients with Type 2 Diabetes and Different Stages of Diabetic Kidney Disease
  Author(s): Anastasia Georgoulidou, Athanasios Roumeliotis, Stefanos Roumeliotis, Ilias Thodis, Vangelis Manolopoulos, Pavlos Malindretos, Kostas Mavromatidis and Ploumis PassadakisAnastasia Georgoulidou, Athanasios Roumeliotis, Stefanos Roumeliotis, Ilias Thodis, Vangelis Manolopoulos, Pavlos Malindretos, Kostas Mavromatidis and Ploumis Passadakis
  
  Adiponectin is an inflammatory cytokine produced by adipose tissue and its protective role has been recognized in the pathogenesis of obesity. A lower concentration in obesity patients is noted, in conditions of resistance to insulin, diabetes mellitus, and CKD. Patients with type 2 diabetes mellitus have a potential risk of atherosclerosis, while low concentrations of adiponectin are considered as predictor for the occurrence of complications in patients with type 2 diabetes. The aim of this study was to investigate in patients with type 2 diabetes mellitus with and without diabetic nephropathy the correlation of adiponectin levels and CKD stage or degree of albuminuria. We studied 119 patients with type 2 diabetes mellitus with different stage of renal function, the levels of plasma adiponectin, and the BMI. A statistically significant difference of plasma adiponectin levels was not.. Read More»
  DOI: 10.4172/2161-0959.1000285

  Abstract PDF