Kalinga Institute of Medical Sciences,
Campus 5, Patia, Bhubaneswar, Odisha 751024
India
Research Article
Comparison of Efficacy of Amlodipine and Cilnidipine on Left Ventricular Hypertrophy amongst Hypertensive Patients
Author(s): Sougata Sarkar, Vartika Srivastava and Manjushree MohantySougata Sarkar, Vartika Srivastava and Manjushree Mohanty
Left ventricular hypertrophy is one of the commonest cardiac sign seen in hypertensive patients. According to American Heart Association and Joint National Committee VIII calcium channel blockers are first line drug in treatment of hypertension. Previous meta-analysis shows Calcium channel blocker can reduce left ventricular hypertrophy by 9-11%. The study was undertaken to evaluate and compare the efficacy of Amlodipine and Cilnidipine on Left ventricular hypertrophy and Systolic function. Total 48 patients were selected and enrolled as study participants. The patients were then divided as (1) Hypertensive group (n=22) and (2) Diabetic hypertensive group (n=26) - selected patients received either Amlodipine (2.5 to 10 mg) or cilnidipine (5 to 20 mg) with or without Angiotensin receptor blockade along with antidiabetic medication. Echocardiography report done to all selected patients .. Read More»
DOI:
10.4172/2167-1095.1000244
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report