India
Research Article
Metabolic Profile of Persons with Newly Diagnosed Diabetes Using either Glycoslated Haemoglobin or Oral Glucose Tolerance Test in Primary Prevention Trials in Asian Indians
Author(s): Arun Raghavan, Nanditha Arun, Snehalatha Chamukuttan, Priscilla Susairaj, Vijaya Lakshminarayanan and Ramachandran AmbadyArun Raghavan, Nanditha Arun, Snehalatha Chamukuttan, Priscilla Susairaj, Vijaya Lakshminarayanan and Ramachandran Ambady
Background: To compare cardio metabolic characteristics of Asian Indians with incident type 2 diabetes diagnosed by Oral Glucose Tolerance Test (OGTT) or by Glycosylated Haemoglobin (HbA1c).
Research Design and Methods: Data from two Indian Diabetes Prevention Studies in persons with Impaired Glucose Tolerance (IGT) was used. In 314 persons, diabetes was diagnosed by OGTT and another 67 persons had only HbA1c values ≥ 6.5% (≥48 mmol/mol). Cardiometabolic characteristics were compared in 3 sub-groups-1: Persons with positive OGTT only (HbA1c<6.5% (<48 mmol/mol) (n=125), 2: Persons with positive HbA1c but negative OGTT (n=67), 3: Those with both HbA1c and OGTT positive (n=189).
Results: Diagnostic sensitivity of HbA1c was 67.2% when compared with OGTT criteria. Prevalence of obesity, abdominal obesity, .. Read More»
DOI:
10.4172/2167-0943.1000209
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report