Journal of Clinical Case Reports

Viktor Grunwald

Publications

• Case Report
  Metastatic Liposarcoma: A Case of Partial Remission with Eribulin in Late Treatment Lines
  Author(s): Viktor Grunwald and Philipp IvanyiViktor Grunwald and Philipp Ivanyi
  
  Liposarcoma, a type of soft tissue sarcoma, represents a therapeutic challenge, in particular in the metastatic setting. This case describes a patient with retroperitoneal liposarcoma that was first treated by surgery and, upon manifestation of metastatic disease, with a series of chemotherapy regimens comprising doxorubicin (line 1), doxorubicin plus ifosfamide (line 2), trabectedin (lines 3 and 4) and dacarbazine (line 5). While transient partial remission was achieved in the first three lines, rapid disease progression was observed in subsequent therapies. After failure of the previous chemotherapy regimens, eribulin was administered (line 6), and partial remission was achieved within five months. However, the occurrence of grade 3 polyneuropathy led to temporary discontinuation of therapy. Overall, metastatic liposarcoma was controlled for twelve months with eribulin treatment in .. Read More»
  DOI: 10.4172/2165-7920.10001109

  Abstract PDF