Journal of Cytology & Histology

Viktoria Gredler

Publications

• Review Article
  B Cells Accumulate in the Cerebrospinal Fluid in Inflammatory Neurological Diseases
  Author(s): Viktoria Gredler and Markus ReindlViktoria Gredler and Markus Reindl
  
  The contribution of B lymphocytes and their products to the pathogenesis of inflammatory diseases of the central nervous system is still not fully understood. Beside their role as precursors of antibody-secreting cells, B cells participate in the regulation of T cell activation through their antigen-presenting capacity, the production of cytokines and chemokines and the formation of ectopic germinal centers in intermeningeal spaces. This article reviews the current knowledge on B cells within the cerebrospinal fluid in inflammatory diseases affecting the central nervous system. Here, we will focus on two prototypical inflammatory diseases of the central nervous system: multiple sclerosis, an autoimmune-mediated inflammatory disease, and infection-triggered inflammation in Lyme neuroborreliosis... Read More»
  DOI: 10.4172/2157-7099.S1-001

  Abstract PDF