Environmental & Analytical Toxicology

Wala Chimela

Publications

• Research Article
  Aspartate Transaminase (AST) Activity in Selected Tissues & Organs of Clarias Gariepinus Exposed To Different Levels of Paraquat
  Author(s): Wala Chimela, Nwibari Mesua and Bawa-Allah AbdulraheemWala Chimela, Nwibari Mesua and Bawa-Allah Abdulraheem
  
  Analyzing the activities of aspartate transaminase in tissues can help detect tissue damage cause by toxicants such as paraquat. The activities of aspartate transaminase (AST) in some tissues and organs of Clarias gariepinus exposed to various levels of paraquat (2, 4, 6 and 8ppm) were studied for a period of thirty (30) days. The tissues and organs investigated include blood plasma, kidney, liver, gills and muscle. The result showed changes in AST activity in the treatment group as compared to the control group; however the increase was not concentration dependent. AST activity was highest in the liver (445.00 ± 0.00IU/L SD) and lowest in the gill (65.00 ± 27.39 IU/L SD) in the control group. There was no significant change in AST activity in the liver across the treatment range. AST activity however declined in the muscle with the lowest at 6ppm of paraquat. There was a si.. Read More»
  DOI: 10.4172/2161-0525.1000214

  Abstract PDF