Institute of Medicine,
Division of Allergy, Immunology and Rheumatology, China Medical University Hospital, Taichung, Taiwan
Research Article
Serum Beta-endorphin Changes in Lumbar Facet Syndrome Treated with Radiofrequency Lumbar Facet Denervation - A Randomized Controlled Study
Author(s): Tsou HK, Kao TH, Tsai PA, Chen HT, Pan HC and Wei JCCTsou HK, Kao TH, Tsai PA, Chen HT, Pan HC and Wei JCC
Background: Lumbar facet joint has been considered a significant source of chronic low back pain (LBP). Radiofrequency (RF) lumbar facet denervation is an effective treatment modality for patients with lumbar facet syndrome (LFS). We propose this protocol to study the effect of RF and the change in serum beta-endorphin level in the treatment of LFS.
Methods: This open-label, parallel, randomized controlled clinical trial enrolled patients with LFS. The study subjects were randomly assigned equally into two arms. The treatment arm received percutaneous RF and the control arm received medical treatment using non-steroidal anti-inflammatory drugs (NSAIDs). Patients were evaluated at days 0, 7 and 28 after randomization. Primary endpoints were the pain visual analogue scale on day 28. Secondary endpoints were visual analogue scale on day 7, qual.. Read More»
DOI:
10.4172/2165-7939.1000340
Journal of Spine received 2022 citations as per Google Scholar report