Key Laboratory of Heilongjiang University of Chinese Medicine,
24 Heping Road, Xiangfang District, Harbin, Heilongjiang, 150040
China
Research Article
GV20 Penetrating GB7 on the Expression of Wnt1 in Brain Tissue of Rats with Intracerebral Hemorrhage
Author(s): Wei Wu, Xiaohong Dai, Wei Zou, Xueping Yu, Wei Teng, Xiaowei Sun, Weiwei Yu, Huihui Ma, Qiuxin Chen, Peng Zhang, Tingting Yu and Peng LiuWei Wu, Xiaohong Dai, Wei Zou, Xueping Yu, Wei Teng, Xiaowei Sun, Weiwei Yu, Huihui Ma, Qiuxin Chen, Peng Zhang, Tingting Yu and Peng Liu
Background: Intracerebral hemorrhage (ICH) is a life-threatening disease that confuses us for centuries. Acupuncture as a kind of Chinese traditional treatment has been empirically established and widely used in clinics in China, especially for stroke victims. Studies proved that GV20 penetrating GB7, a kind of needling manipulation, with which a needle is inserted into GV20 and then to GB7 under the scalp, is especially effective on the treatment of this disease. Wingless-type1 (Wnt1) is a key factor of Wnt/β-catenin signal pathway, which could promote regeneration and remodeling of neural function after ICH by affecting proliferation and differentiation of the neural stem cells (NSCs). The study on the expression of Wnt1 induced by GV20 penetrating GB7 may give out the theoretical principle of the treatment.
Objective: The goal of this w.. Read More»
DOI:
10.4172/2161-0444.10485
Medicinal Chemistry received 6627 citations as per Google Scholar report