Nuclear Medicine & Radiation Therapy

William Thompson

Publications

• Research Article
  Predictive Factors for Radiation Pneumonitis in Patients Receiving Intensity-modulated Radiation Therapy for Thoracic Malignancy
  Author(s): Aleks Sorra E II, Thomas Schroeder, Ben Liem, William Thompson and Sagus SampathAleks Sorra E II, Thomas Schroeder, Ben Liem, William Thompson and Sagus Sampath
  
  Purpose: It is unknown whether established dose-volume parameters predictive of radiation pneumonitis (RP) are applicable to multiple disease sites. We investigated the factors associated with RP in a heterogeneous population of patients receiving thoracic radiation. Methods and materials: Ninety-nine patients who received thoracic radiation with helical tomotherapy were included in this retrospective chart review. Correlation studies were performed and significant clinical and dosimetric factors predictive for grade ≥ 3 RP were assessed using Cox multivariate analysis (MVA). Results: Fifty-two patients developed RP (grade 1-5), the majority having grade 1 toxicity. Five patients experienced grade ≥ 3 RP. Eleven patients developed ≥ 2 RP. The mean time to RP was 3 months. The sole predictor of R.. Read More»
  DOI: 10.4172/2155-9619.1000149

  Abstract PDF