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Journal of Tissue Science and Engineering

ISSN: 2157-7552

Open Access

Wolever JD


Tanzania

Publications
  • Research Article
    Structural Alterations in Scaffold Architecture in Response to Mechanical Stimuli
    Author(s): Blackstone BN, Wolever JD and Powell HMBlackstone BN, Wolever JD and Powell HM

    Background: Though mechanical stimulation has been shown to improve mechanical properties of many engineered tissues, little is known about the impact of stimulation on scaffold architecture. In engineered tissues where the scaffold comprises a large portion of the tissue, mechanical signals are transferred from the external environment through the scaffold to the cells. Thus, a greater understanding of the architectural changes a scaffold experiences during mechanical stimulation may provide new knowledge on the communication between the cells and scaffold, during dynamic in vitro tissue development. Methods: Two distinct scaffold architectures were fabricated via lyophilization or electro-spinning of collagen. Pore size of lyophilized scaffolds, fiber diameter and inter-fiber distance of electrospun scaffolds, and ultimate tensile strength, linear s.. Read More»
    DOI: 10.4172/2157-7552.1000122

    Abstract PDF

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Citations: 807

Journal of Tissue Science and Engineering received 807 citations as per Google Scholar report

Journal of Tissue Science and Engineering peer review process verified at publons

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