Indiana
Research Article
Grading of Peripheral Cytopenias due to Splenomegaly and Hepatitis B Cirrhotic Portal Hypertension
Author(s): Yunfu Lv, Wan Yee Lau, Xiaoyu Han, Xiaoguang Gong, Qingyong Ma, Shunwu Chang, Hongfei Wu, Yejuan Li and Jie DengYunfu Lv, Wan Yee Lau, Xiaoyu Han, Xiaoguang Gong, Qingyong Ma, Shunwu Chang, Hongfei Wu, Yejuan Li and Jie Deng
Background: Splenomegaly due to hepatitis B cirrhotic portal hypertension is common in clinical practice, and it is often complicated by monolineage or multilineage cytopenias. We attempted to answer the following questions based on our 20 years of observation and research: can peripheral cytopenias be graded and what are the effects of peripheral cytopenia grades on clinical outcomes?
Objectives: This study aimed to investigate the grading of peripheral cytopenia in patients with splenomegaly due to hepatitis B cirrhotic portal hypertension and its effect on clinical outcomes.
Methods: Data from 330 patients with splenomegaly due to hepatitis B cirrhotic portal hypertension were collected from January 1991 to December 2011. All data were analysed with SPSS 13.0. Univariate and multivariate analyses were performed... Read More»
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report