People’s Hospital of Chongqing City,
China
Case Report
To Investigate the Impact of Laparoscopic Resection of Colorectal Carcinoma on the Peritoneal Metastases of Cancer
Author(s): Xin Wang, Anren Sun, Linkang Xiao and Rong YangXin Wang, Anren Sun, Linkang Xiao and Rong Yang
Objective: To explore the effect of laparoscopy on cancer cells and the expressions of adhesion molecules (ICAM‐1, CD44v6 & integrin β1) in peritoneal tissue and abdominal rinse in patients with colorectal carcinoma (CC).
Methods: A total of 65 CC cases undergoing radical resection at our hospital were analyzed. They were divided into two groups of LAP (laparoscopy, n=35) and OP (open surgery, n=30). Peritoneal tissues were collected at incision and beyond .Also abdominal rinse was collected before tumor resection and abdomen closure. The expressions of adhesion molecules (ICAM‐1 ,CD44v6 & integrin beta 1) in peritoneal and abdominal cavities of two groups were detected by immunohistochemistry and double‐antibody sandwich ABC‐ELISA. And cancer cells in abdominal rinse were detected by peritoneal lavage cyto.. Read More»
DOI:
10.7438/1584-9341-12-2-8
Journal of Surgery received 288 citations as per Google Scholar report