China
Research Article
Association between Hematocrit Level and the Development of Non-Alcoholic Fatty Liver Disease in Chinese Adults: A 5-Year Study
Author(s): Xuekui Liu, Jun Liang, Qinqin Qiu, Fei Teng, Yu Wang, Yan Zhu, Ying Pei and Yuting SunXuekui Liu, Jun Liang, Qinqin Qiu, Fei Teng, Yu Wang, Yan Zhu, Ying Pei and Yuting Sun
Non-alcoholic fatty liver disease (NAFLD) is recognized as a major cause of liver-related morbidity and mortality. The aim of this study was to examine the longitudinal association between baseline hematocrit (HCT) level and the development of NAFLD in Chinese adults. We performed a prospective cohort study of 2798 healthy Chinese adults without NAFLD at baseline. A Cox proportional hazards model was used to determine hazard ratios for NAFLD incidence in two groups determined by baseline hematocrit levels (group A, HCT <49%; group B, HCT ≥ 49%). During 10346.5 person-years of follow-up, 474 (16.9%) NAFLD cases developed between 2008 and 2012. After adjusting for multiple covariates and change in the covariates during the follow-up period, the hazard ratios (95% confidence interval) for NAFLD incidence when comparing group B with group A were 1.17 (1.03-1.31) and 1.70 (1.26-2.31).. Read More»
DOI:
10.4172/2167-0943.1000220
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report