Molecular Biology: Open Access

Yang Liu

Publications

• Research Article
  Genetic Diversity and Drug Resistance of 133 Mycobacterium tuberculosis Isolates from Jiangxi Province, China
  Author(s): Minghui Zhao, Yang Liu, Kaiming Liu, Kanglin Wan, Zhiping Lv, Shaohua Tu, Yun Liao and Lin MaMinghui Zhao, Yang Liu, Kaiming Liu, Kanglin Wan, Zhiping Lv, Shaohua Tu, Yun Liao and Lin Ma
  
  The genotypes of Mycobacterium tuberculosis (M. tuberculosis) have been found to differ in their resistance to different drugs. Although there is a high incidence of tuberculosis (TB) in Jiangxi, knowledge of the genotypes of M. tuberculosis in this province is limited in recent years. In this study, we investigated the relationship between genetic diversity and drug resistance in M. tuberculosis isolates collected from Jiangxi during January to October, 2014. A total of 133 M. tuberculosis isolates collected from the Jiangxi Chest Hospital were genotyped using both spacer oligonucleotide typing (spoligotyping) and 24-locus mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR). The resistance of these isolates to four first-line, and four second-line, anti-TB drugs, namely, isoniazid, rifampicin, ethambutol, strep.. Read More»
  DOI: 10.4172/2168-9547.1000157

  Abstract PDF