Molecular and Genetic Medicine

Yang M

Publications

• Research Article
  Frequency of Chromosomal Abnormalities in Subpopulations of Infertile Males among Chinese Hakka Population
  Author(s): Zhao P, Gu X, Wang H and Yang MZhao P, Gu X, Wang H and Yang M
  
  The frequency of chromosomal abnormalities is supposed to be elevated in infertile males as well as shown negative correlation of sperm concentration. Cytogenetic analysis, recommended by guidelines in infertile men, is expensive. Hence, it may be good for recognize riskiest men with chromosomal abnormalities, potentially by analyzing sperm concentration outside of the parameters. Aim to evaluate the frequency of chromosomal abnormalities in different subpopulations among Hakka population, we assessed several clinical parameters in infertile men. A total of 1291 azoospermic men and men apply for in-vitro fertilization (IVF) treatment, were analyzed for semen parameters, hormone levels, Y chromosome microdeletions and medical history, related to chromosomal abnormalities. Chromosomal abnormalities were detected 46 of 1291 men (3.6%) in our study. Correlation was no shown between chromosom.. Read More»
  DOI: 10.4172/1747-0862.1000352

  Abstract PDF