Cancer Science & Therapy

Yasuki Iwasaki

Publications

• Research Article
  MK615, A Compound Extract from the Japanese Apricot ?Prunus mume? Inhibits In vitro Cell Growth and Interleukin-8 Expression in Non-small Cell Lung Cancer Cells
  Author(s): Noriaki Sunaga, Katsuya Hiraishi, Tamotsu Ishizuka, Kyoichi Kaira, Yasuki Iwasaki, Fumie Jimma and Masakazu AdachiNoriaki Sunaga, Katsuya Hiraishi, Tamotsu Ishizuka, Kyoichi Kaira, Yasuki Iwasaki, Fumie Jimma and Masakazu Adachi
  
  The Japanese apricot “Prunus mume,” which is also known as the Ume fruit in Japan, is a centuries-old traditional Japanese medicine, and it is a commonly consumed food. MK615, a compound extract from Ume fruits, has been shown to have anti-tumor and anti-inflammatory effects. In this study, we assessed the effects of MK615 on the in vitro growth of nine non-small cell lung cancer (NSCLC) cell lines and the HBEC4 immortalized bronchial epithelial cell line. While MK615 inhibited the in vitro cell growth of the majority of the NSCLC cell lines, the growthinhibitory effects varied among the cell lines, and some cell lines exhibited MK615 resistance. In the H1299 and H157 NSCLC cell lines that are highly sensitive to MK615, the induction of autophagy was observed after MK615 treat.. Read More»
  DOI: 10.4172/1948-5956.S11-002

  Abstract PDF