Journal of Forensic Research

Yingyuan Wang

Publications

• Research Article
  Postmortem Redistribution of Lidocaine after Epidural Anesthesia Accidental Death
  Author(s): Zhiwen Wei, Jie Yu, Chao Zhang, Juan Jia, Jie Cao, Yujin Wang, Cairong Gao, Yingyuan Wang and Keming YunZhiwen Wei, Jie Yu, Chao Zhang, Juan Jia, Jie Cao, Yujin Wang, Cairong Gao, Yingyuan Wang and Keming Yun
  
  Epidural anesthesia is often used form in Chinese primary hospitals and lidocaine is the most favorite anesthetic. Fatalities due to epidural anesthesia accident and lidocaine overdose are often happened, but there still have not obvious evidence to indicate the real reason of death according to the concentration of lidocaine in postmortem blood because the postmortem redistribution (PMR). An animal models using dogs has been developed, whereby the dogs received an intravenous, subarachnoid, and epidural injection of lidocaine (75 mg/kg body weight). The dogs were placed at room temperature after sacrifice. The cardiac blood, inferior vena cava blood, liver and cerebrum samples were collected at 0 h, 1 h, 4 h, 8 h, 24 h, 48 h and 72 h postmortem with the same animal’s corpse. The lidocaine is easier diffusion from canalisvertebralis to cardiac blood in subarachnoid administratio.. Read More»
  DOI: 10.4172/2157-7145.1000363

  Abstract PDF