Indiana
Research Article
Neuromyelitis Optica Spectrum Disorder and Neurosyphilis Coexist in A Chinese Woman
Author(s): Fulan Shan, Youming Long, Yongxiang Fan, Mengyu Chen, Yangbo Zheng and Cong GaoFulan Shan, Youming Long, Yongxiang Fan, Mengyu Chen, Yangbo Zheng and Cong Gao
Background: Neuromyelitisoptica spectrum disorder (NMOSD) is a series of central nervous system diseases with positive aquaporin-4 antibody. And neurosyphilis is a manifestation of the late syphilis. Although Neuromyelitisoptica (NMO) following syphilis has been previously reported, transverse myelitis and neurosyphilis in the same patient with positive aquaporin-4 antibody has never been mentioned.
Method: We presented the coexistence of NMOSD and syphilis in a 72-year-oldChinese woman and analyzed the relationship of these two diseases. The pertinent literatures were also reviewed.
Result: Previous studies showed that syphilitic myelitis might be more frequent in male than in female and it tended to be asymptomatic. However our case was a woman who experienced acute attack, with positive AQP4 antibody. Therefore,.. Read More»
DOI:
10.4172/2155-9929.1000198
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report