Journal of Nephrology & Therapeutics

Yu Zhou

Publications

• Case Report
  Rituximab for Treatment of Focal Segmental Glomerulosclerosis in a Child: A Case Report
  Author(s): Zhengkun Xia, Yu Zhou, Yuanfu Gao, Zhongmin Fan, Chunlin Gao, Song Mao, Xu He, Zhuo Shi, Tao Sun, Pei Zhang, Hongjun Peng and Min XuZhengkun Xia, Yu Zhou, Yuanfu Gao, Zhongmin Fan, Chunlin Gao, Song Mao, Xu He, Zhuo Shi, Tao Sun, Pei Zhang, Hongjun Peng and Min Xu
  
  Objective: To study the efficacy of rituximab in children with focal sclerosing glomerulonephritis (FSGS). Case Report: Before treatment, blood biochemistry, hepatic and renal function, differential white cell counts, immunoglobulins and the complement system were assessed. Promethazine (0.5-1 mg/kg) and methylprednisolone (0.1-0.3 mg/kg) were administered intravenously 30 min and 5-10 min before the rituximab infusion. Rituximab (0.27 g) was diluted in 300 ml glucose solution and initially administered at 50 ml/hr the rate increased to 50 ml/hr every 30 min after no side effects occurred in the first hour. A second dose was given one month later. During treatment, prednisone (30mg) was taken on alternate days. Benazepril (3.3 mg) was administered every day with one chongcao capsule. Homemade ershenkang was given three times a day. Outcome: Eyelid and limb edema declined two weeks aft.. Read More»
  DOI: 10.4172/2161-0959.S1-009

  Abstract PDF