Journal of Clinical Case Reports

Yuka Hosotani

Publications

• Case Report
  Anti-Cancer Drug Nab-Paclitaxel May Exacerbate Corneal Epithelial Disorder
  Author(s): Yuka Hosotani, Hiroto Ishikawa, Kumiko Miyanaga and Fumi GomiYuka Hosotani, Hiroto Ishikawa, Kumiko Miyanaga and Fumi Gomi
  
  Purpose: To report 2 cases of corneal disorder after cancer treatment with nab paclitaxel. Methods: Retrospective review of 2 cases. Case presentation: Case 1 was a 55-year-old female who presented with blurred vision. She underwent cancer treatment in the form of combination therapy with nab-paclitaxel, trastuzumab and pertuzumab for breast cancer 2 weeks before. An ophthalmoscopic examination showed an atypical corneal epithelium invasion in both eyes. The corneal disorder was resolved following discontinuation of nab-paclitaxel. Case 2 had a pancreatic cancer and she presented with an atypical corneal epithelium invasion in both eyes after treatment with S-1 and gemcitabine hydrochloride. The corneal disorder might be caused by S-1, so S-1 treatment was replaced by nab-paclitaxel. The corneal disorder improved t.. Read More»
  DOI: 10.4172/2165-7920.10001002

  Abstract PDF