Human Genetics & Embryology

Yusuf Yasar

Publications

• Research Article
  The Frequency and Types of Chromosomal Aberrations in the Patients with Hypogonadism
  Author(s): Osman Demirhan, Nilgün Tanrıverdi, Dilara Süleymanova, Nesrin Cetinel and Yusuf YasarOsman Demirhan, Nilgün Tanrıverdi, Dilara Süleymanova, Nesrin Cetinel and Yusuf Yasar
  
  Objectives: Hypogonadism is the clinical manifestation of the impaired function of the testes and the ovaries, and is either due to endocrinological problems or chromosomal abnornlalities (CA). Chromosomal analysis is one important piece in the hypogonadism individuals, and becomes essential from the clinical point of view. Design: To determine the frequency, types of CAs in a hypogonadism population. Materials and method: The current study was a retrospective analysis to examine the CAs and prevalence in 64 cases with unexplained hypogonadism problem. The samples were cultured routinely for the karyotype analysis using G banding. Results: A total of 64 individuals with infertility was analysed. The karyotype results were normal in 52 (81.2%) of 64 individuals. However, CAs were detected in 12 (18.8%) of all individuals. The 15.6% of these CAs was numerical aberrations, and also struc.. Read More»
  DOI: 10.4172/2161-0436.1000124

  Abstract PDF