Japan
Research Article
Clinical Factors Relating to Cervical Body Volume Reduction during Curative External Beam Radiation Therapy for Head and Neck Cancer
Author(s): Ken Takeda, Suguru Dobashi, Shinya Komori, Koichi Chida, Noriyuki Kadoya, Satoshi Kida, Kengo Ito, Toshiyuki Sugawara, Masaki Kubozono, Rei Umezawa, Yojiro Ishikawa, Takaya Yamamoto, Maiko Kozumi, Noriyoshi Takahashi, Yu Katagiri, Yusuke Onozato, Takayuki Kanai, Kiyokazu Sato, Kazuma Kishi, Haruo Matsushita, Takenori Ogawa, Yukio Katori and Keiichi JinguKen Takeda, Suguru Dobashi, Shinya Komori, Koichi Chida, Noriyuki Kadoya, Satoshi Kida, Kengo Ito, Toshiyuki Sugawara, Masaki Kubozono, Rei Umezawa, Yojiro Ishikawa, Takaya Yamamoto, Maiko Kozumi, Noriyoshi Takahashi, Yu Katagiri, Yusuke Onozato, Takayuki Kanai, Kiyokazu Sato, Kazuma Kishi, Haruo Matsushita, Takenori Ogawa, Yukio Katori and Keiichi Jingu
Purpose/Objectives: Substantial cervical body volume reduction (CBVR) occurs during fractionated external beam radiation therapy (EBRT) for head-and-neck cancer (HNC) and could have potential dosimetric influences. This study aims to investigate measurable clinical factors before treatment initiation correlating with CBVR during curative EBRT in HNC patients, and to determine which patients receive the great benefit from routine adaptive radiation therapy (ART).
Materials/Methods: Fifty-six patients with oropharyngeal squamous cell carcinoma (OSCC) and 67 patients with hypopharyngeal squamous cell carcinoma (HSCC) had received curative EBRT between 2006 and 2013 were enrolled. For EBRT planning, computed tomography (CT) images were acquired before EBRT initiation and between two to seven weeks after the start of EBRT for replanning in each patient. A MATLAB program was used to.. Read More»
DOI:
10.4172/2155-9619.1000203
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report