Journal of Dermatology and Dermatologic Diseases

Zahra Jafarian

Publications

• Research Article
  Serum Homocysteine: Is it a Biomarker for Vitiligo?
  Author(s): Fariba Ghalamkarpour, Zahra Jafarian, Hoda Einollahi and Shima YounespourFariba Ghalamkarpour, Zahra Jafarian, Hoda Einollahi and Shima Younespour
  
  Background: Vitiligo is a common, multifactorial, polygenic pigmentary disorder with a complex pathogenesis. Free radical and immune mediated damage of melanocytes are the most probable pathological mechanism. There have been several conflicting reports on the blood levels of vitamin B12, folate and homocysteine in vitiligo and its severity. Because of relation between vitamin B12, RBC folate and homocysteine, we checked serum level of vitamin B12 and RBC folate as well. Methods: In this study a total of 50 patients and 53 age and sex matched healthy controls were enrolled. Serum vitamin B12, homocysteine and RBC folate are checked. Disease activity was assessed by Vitiligo Disease Activity (VIDA) score and disease severity assessed by VASI score. Results: The two groups did not differ significantly in RBC folate concentrations and serum levels of vitamin B12. Patients with vitiligo h.. Read More»
  DOI: 10.4172/2376-0427.1000172

  Abstract PDF