Poland
Research Article
The Significance of the Lymphocytes Infiltration and Endothelialdependent Angiogenesis in Choroidal Melanomas
Author(s): Joanna Reszec, Zalewska Renata, Proniewska-Skretek Ewa and Chyczewski LechJoanna Reszec, Zalewska Renata, Proniewska-Skretek Ewa and Chyczewski Lech
Objective: Posterior uveal melanoma is the most common primary intraocular malignant tumor in adults. Despite the clinical significant treatment, still many patients die because of unpredictable metastases. It is difficult to predict clinical outcome in individual cases of ocular melanoma basing only on the intraocular size, because of the spectrum of clinical, morphologic, and cytologic changes and lack of discrete stages.
Design: The aim of the study was to evaluate CD3, CD20 and CD34 expression within choroidal melanoma in
correlation with clinic and pathological features. Participants: 35 cases of choroidal melanoma were evaluated.
Methods: Immunohistochemical reaction was used to evaluate CD3 and CD20 (T and B cells markers) and
CD34 (endothelial cells marker) expression, with positive and negative controls. Obtained results were estimated under the .. Read More»
DOI:
10.4172/2157-7099.1000200
Journal of Cytology & Histology received 2334 citations as per Google Scholar report