Pulmonary & Respiratory Medicine

Zhang WP

Publications

• Case Report
  The Effects of Inverse Ratio Ventilation with PEEP on Respiratory Function and Inflammatory Cytokines in Patients during One-lung Ventilation
  Author(s): Zhang WP and Zhu SMZhang WP and Zhu SM
  
  Background: Hypoxemia is the most common complication during one-lung ventilation (OLV). Inverse ratio ventilation (IRV) may lead to intrinsic positive end-expiratory pressure (PEEP) and improve oxygenation in acute respiratory distress syndrome, so we investigated whether volume-controlled IRV with external PEEP could improve hypoxemia, reduce the risk of acute lung injury during OLV. Methods: Sixty patients undergoing one-lung ventilation for open thoracoctomy were randomly divided into IRV group and control group (n = 30). All patients were initially ventilated with a tidal volume of 8 mL/kg, an inspiratory: expiratory (I:E) ratio of 1:2 and a respiratory rate of 12 breaths/min in 100% oxygen without PEEP. During OLV, lungs were ventilated either with I:E of 2:1 (IRV group) or 1:2 (control group) with an actual tidal.. Read More»
  DOI: 10.4172/2161-105X.1000329

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