Molecular Biomarkers & Diagnosis

Zhen Xu

Publications

• Research Article
  New Markers to Explore Spontaneous Bacterial Peritonitis
  Author(s): Fang Fang Wei, Xiaohong Zhang, Zhen Xu and Shaoquan ZhangFang Fang Wei, Xiaohong Zhang, Zhen Xu and Shaoquan Zhang
  
  Spontaneous Bacterial Peritonitis (SBP) is an ascitic fluid infection without a definitive, surgically treatable, intraabdominal source, accounting for 10 to 30% of cirrhotic patients with ascites. To explore new methods of diagnosing Spontaneous Bacterial Peritonitis (SBP), we prospectively studied 19 Acute-on-Chronic Hepatitis B Liver Failure (ACHBLF) patients with or without Spontaneous Bacterial Peritonitis and 17 Hepatitis B Virus (HBV)-related Liver Decompensated Cirrhosis patients with or without Spontaneous Bacterial Peritonitis. Patients were separated into two groups: SBP group (n=14), non SBP group (n=22). A paracentesis of ascetic fluid was performed. The levels of 40 cytokines in ascetic fluid were measured by using RayBio® Human Cytokine Antibody Array. The results indicated that the levels of RANTES, EOTAXIN EOTAXIN-2, IL-1βand MIP-1αwere higher in the as.. Read More»
  DOI: 10.4172/2155-9929.1000200

  Abstract PDF