Pulmonary & Respiratory Medicine

Zifeng Yang

Publications

• Short Communication
  Assess the Possibility of Screening and Supervising Influenza A (H7N9) Virus-Infected Patients via Rapid Point-of-Care-Test Kit with Upper or Lower Respiratory Specimens
  Author(s): Zhengtu Li, Li Li, Shiguan Wu, Xiaobo Li, Runfeng Li, Wenbo Huang, Sihua Pan, Wenda Guan, Jicheng Huang and Zifeng YangZhengtu Li, Li Li, Shiguan Wu, Xiaobo Li, Runfeng Li, Wenbo Huang, Sihua Pan, Wenda Guan, Jicheng Huang and Zifeng Yang
  
  The purpose of this study was to assess the possibility of screening and supervising influenza A (H7N9) virus infected patients via rapid point-of-care-test kit with upper or lower respiratory specimens. Here, we demonstrate that the POCT kits can detect H7N9 virus (Guangzhou strain) in different type of samples, which obtained from upper and lower respiratory tract, via the simulated experiment. The detection limit ranged from 4 to 6 log10TCID50/mL and 2.78 × 107 to 1.05 × 108 copies/mL in PBS and nasopharyngeal swab solution (NSS) solutions respectively. Furthermore, the detection ranges were enhanced by 0.5 or 1 log10TCID50/mL in BALF or sputum solution (SS) diluents for some parts of the POCT kits. Furthermore, we observed that there were higher replication and longer screening of H7N9 virus in lower respiratory tract (LRT) samples, su.. Read More»
  DOI: 10.4172/2161-105X.1000371

  Abstract PDF