Journal of Clinical Case Reports

Department of Endocrinology, Endocrinologist at Queen Rania Children Hospital, Jordanian Royal Medical Services, Amman, Jordan

Publications

• Case Report   
  Jordanian Girl with Juvenile Granulose Cell Tumor Presented as Precocious Puberty: A Case Report
  Author(s): Fadi Farhan Ayyash, Abdalrazzaq Ahmad Alyassen*, Samer Sukre Karadsheh, Ibrahim Mohammad Sawalha, Alia Musa Al-Khlaifat, Alaeddin Ali Saleh, Omar Yassen Ashokaibi and Mustafa Ogleh Al-Haji
  
  Objective: Our objective is to explain precocious puberty, type, etiology, investigation, how to differentiate between central and peripheral precocious puberty, and focus on one of the rarest causes of precocious puberty. Case report: In our case of precocious puberty, a two-year-old female presented with bilateral breast enlargement, vaginal secretion, pubic hair, and abdominal swelling. An abdominal and pelvic CT shows a very large ovarian mass. Asalpino-oophorectomy was carried out with regression of symptoms and signs and improvement in laboratory exams. The biopsy showed Juvenile Granulosa Cell Tumors (JGCT). Discussion: Due to an increase in the levels of estradiol and no increase in the gonadotropins (LH, FSH), advanced bone age and height age are compatible with the chronic age of 2 years old, .. Read More»
  DOI: 10.37421/2165-7920.2021.11.1463

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