Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
Research Article
Dynamic Changes of Troponin and Creatine Phosphokinase in Acute
Myocarditis and Non-ST Elevation Myocardial Infarction
Author(s): Koren O*, Rozner E, Abu-Daoud I and Turgeman Y
Background: Myocarditis and acute Myocardial Infarction pose a daily diagnostic dilemma. Magnetic resonance
imaging and endomyocardial biopsy are the gold standard for definite diagnosis but are rarely performed routinely.
Troponin and Creatine phosphokinase (CPK) are elevated in both diseases and could not be used for proper
discrimination. We analyzed the dynamics of these serum markers during acute setting by analyzing the tangent
slope of their level curve over time.
Methods: We conducted a retrospective cohort study in our medical center. Records of approximately 1,300
patients hospitalized from January 2011 to December 2016 were examined. A total of 193 patients were found to be
eligible for the study and were divided into two groups: Myocarditis group (n=133, 69%) and non-ST elevation
myocardial infarction gr.. Read More»
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report