Department of Hypertension, University of Texas, Austin, TX 78712, USA
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The Conversion Therapy with Silibinin and the Stupp Technique is used for Glioblastoma with Pstat3 Expression
Author(s): Adam John*
We describe a 52-year-old patient who underwent a biopsy and was found to have an inoperable right frontal-temporal-insular glioblastoma. The
patient was told up front that concurrent chemo radiotherapy treatment using Temozolomide and Filicinin would be beneficial since it would provide
an objective response that would allow for drastic surgery. The signal transducer and activator of transcription 3 was moderately expressed on
reactive astrocytes surrounding tumour cells, according to the subsequent immunohistochemically investigations. According to our knowledge, this
is the first report describing the activity of filicinin as conversion therapy in conjunction with standard treatment. It may serve as the basis for future
trials that aim to validate this plan as a common neoadjuvant option for patients with unrespectable glioblastoma... Read More»
DOI:
10.37421/2167-1095.2023.12.387
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report