Journal of Clinical Case Reports

Senior Resident, Department of Paediatrics, King George’s Medical University, Lucknow, Uttar Pradesh, India

Publications

• Case Report   
  System Onset Juvenile Idiopathic Arthritis Evolving into Macrophage Activation Syndrome in a Child with Pyrexia of Unknown Origin
  Author(s): Sanjukta Mukhopadhyay* and Ajitesh Singh
  
  Macrophage activation syndrome is a potentially life-threatening complication of rheumatic diseases. Here, we report the case of a 4-yearold boy who presented with fever for 5 months, initially moderate-high grade, abdominal pain for 3 months, and pain in BL knee and ankle joints for 2 months. On examination, the child had multiple cervical lymphadenopathies and no organomegaly. The differential of disseminated tuberculosis, lymphoma, and juvenile idiopathic arthritis. The initial blood count was normal. The Chest X-Ray was also normal. Bone marrow examination showed normal hematopoiesis. The excisional biopsy of the cervical lymph node showed reactive lymphadenitis. During the course of hospitalization, the patient developed high-grade fever with hepatosplenomegaly and swelling of BL ankle and knee joints. The blood count at 2 weeks suggested pancytopenia, and.. Read More»
  DOI: 10.37421/2165-7920.2022.12.1540

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