Journal of Morphology and Anatomy

Department of Anatomy, Ladoke Akintola University of Technology, Ogbomoso, Nigeria

Publications

• Research Article   
  Neurodegenerative Changes in the Cerebral Cortex of Adult Wistar Rats Following Lead Induced Oxidative Damage
  Author(s): Ajibade AJ* and Akinrinade SO
  
  Lead is among the chemical compounds that have been reported to cause devastating problem worldwide. The primary site of action of lead is the central nervous system. This study investigated some effects of lead acetate on the cerebral cortex of adult Wistar rats. Thirty six adult Wistarrat of both sexes weighing between 120 g-250 g were randomly grouped into four groups of nine animals per group. Group A rats which was the control was maintained on standard feed and distilled water for 28 days, group B rats were treated with 10 mg/kg of lead acetate for 28 days, group C rats were treated with 20 mg/kg of lead acetate for 28 days and group D rats were also treated with 40 mg/kg of lead for 28 days. The lead acetate solution was administered orally on daily basis. The weights of the Wistar rats was recorded on weekly basis using a sensitive balance (before and during the weeks of a.. Read More»
  DOI: 10.37421/2684-4265.2021.s2.001

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