Addenbrooke’s Hospital, Cambridge University Hospitals, Robinson Way, Trumpington, Cambridge CB2 0AX, UK
Case Report
When No More Investigations are Left: A Probable Case of Primary Angiitis of the Central Nervous System
Author(s): Minesh Patel, Mohamed Rashad Ramali*, Saad Ahmed, Edward Needham, Imtiaz Ahmed and Alasdair Coles
Primary angiitis of the CNS (PACNS) is a distinct form of cerebral vasculitis, the former being confined to the central nervous system (CNS) with no
systemic involvement. Diagnosing PACNS is challenging due to its varied presentation and rarity. We describe a case highly suggestive of PACNS
which despite extensive investigation could not be confirmed even on histology but responded to immunosuppression. We present a 69-year old
man who presented to the emergency department (ED) with acute confusion. Initial magnetic resonance (MR) imaging of the head had shown
ischaemic infarcts and haemorrhages. Cerebrospinal fluid (CSF) analysis and serological work-up had ruled out a systemic vasculitis and an
infectious disease to account for the presentation. Computerised tomography (CT) angiography nor digital subtraction angiography had reported
any evidence of vasculopa.. Read More»
DOI:
10.37421/2471-9544.2023.9.175
Journal of Vasculitis received 83 citations as per Google Scholar report