Department of Bioinformatics, University of North Carolina, Chapel Hill, USA
Mini Review
Bioinformatics Approaches for Drug Repurposing in Rare Diseases
Author(s): Alex John*
Drug repurposing, also known as drug repositioning, offers a promising strategy for identifying new therapeutic uses for existing drugs. In the
context of rare diseases, where traditional drug discovery approaches face significant challenges, bioinformatics plays a critical role in facilitating
the repurposing of drugs to address unmet medical needs. This review examines bioinformatics approaches for drug repurposing in rare diseases,
highlighting the methodologies, data sources, and computational tools used to identify potential candidates. By leveraging omics data, network
analysis, machine learning, and computational modeling, bioinformatics enables the systematic exploration of drug-disease associations and
the prioritization of repurposing candidates based on biological relevance and therapeutic potential. Despite the complexity and heterogeneity
of rare d.. Read More»
DOI:
10.37421/2952-8100.2024.07.449
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