Department of Infectious Disease, Apollo First Med Hospitals, Chennai, India
Review Article
Neurotoxicity of Commonly Employed Antimicrobial Agents: A Review
Author(s): Subramaniam Srinivasan and Allimuthu Nithyanandam*
Antimicrobial agents are the most frequently used pharmacological agents by a practising clinician. Many of the commonly used antibiotics are well tolerated.
They do have side effects either idiosyncratic or dose dependent. Special caution is needed on monitoring their neurotoxic effects as if not recognized promptly,
these may be confused with other neurological states therefore ending up in complications. The practising clinician in most countries, initiates’ treatment based
upon clinical findings and does not have the luxury of getting confirmatory laboratory results in a timely manner. Factors influence neurotoxicity include old age,
decreased renal function, nutritional status, use of other drugs that lower seizure threshold and damage to the blood brain barrier. The role of genetic factors
though has been suggested, their effects have not been fully determin.. Read More»
DOI:
10.4172/2329-6895.10.10.520
Neurological Disorders received 1343 citations as per Google Scholar report