Journal of AIDS & Clinical Research

Department of Human and Health Sciences, Swansea University, Swansea, UK

Publications

• Mini Review   
  RISPR−Based Gene Editing in HIV/AIDS Treatment: Recent Developments
  Author(s): Allyson Rogers*
  
  Despite significant efforts to prevent and treat HIV-1 infection, HIV/AIDS continues to pose a significant threat to human health worldwide. Even though combination antiretroviral therapy (cART) can stop HIV-1 from reproducing, it can't get rid of the proviral DNA that is embedded in the human genome. Because of this, it needs to be taken for the rest of one's life and may cause side effects. Cas9-related gene-editing systems, which are clustered regularly interspaced short palindromic repeat (CRISPR)-associated nuclease 9 (Cas9) related, have been developed and designed as effective treatments for HIV-1 infection in recent years. However, new gene-targeting tools, such as base editor, prime editor, SHERLOCK, DETECTR, PAC-MAN, ABACAS, and pfAGO, have been developed and improved for the purpose of detecting pathogens and correcting diseases. These tools are deri.. Read More»
  DOI: 10.37421/2168-9768.2022.13.915

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