Chemical Sciences Journal

Department of Toxic and Narcotic Drugs, Alexandria University, Alexandria, Egypt

Publications

• Research Article   
  Synthesis, Characterization and Fluorescence of Novel Bromazepam Derivatives
  Author(s): AM Elessawy*, AA El-Barbary and Eman A ElBastawissy
  
  New bromazepam derivatives namely; 7-bromo-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepine -2-thione and 7-bromo-1-(4,6- dichloro-1,3,5-triazin-2-yl)-5-(pyridin-2-yl)-1,3-dihydro-2H-benzo[e] [1,4]diazepin-2-one have been prepared and characterized by spectroscopic methods (FT-IR, 1H-NMR, UV-visible and EI-mass). Furthermore, the fluorometric method has been developed to detect bromazepam in biological fluid. The new methods are based on measuring excitation and emission spectra of the reaction of bromazepam with cyanuric chloride in pyridine solution compared with excitation and emission spectra free bromazepam in methanolic solution... Read More»
  DOI: 10.37421/2150-3494.2024.15.3.329

  Abstract HTML PDF