Department of Vasculitis, University of Bakersfield, 9001 Stockdale Hwy, Bakersfield, CA 93311, USA
Mini Review
Vasculitis and Cardiovascular Complications: Exploring the Link and Potential Interventions
Author(s): Amber Valerie*
As a consequence, patients with vasculitis are at an increased risk of cardiovascular complications, including coronary artery disease, myocardial infarction, stroke, and peripheral artery disease. Several mechanisms contribute to the heightened cardiovascular risk in vasculitis patients. Chronic inflammation, a hallmark of vasculitis, plays a crucial role in the development and progression of atherosclerosis, the main underlying cause of cardiovascular complications. Inflammation leads to increased endothelial permeability, adhesion molecule expression, and recruitment of immune cells, initiating the formation of atherosclerotic plaques. Additionally, vasculitis-associated vasculopathy and vasospasms can further compromise blood flow and promote thrombotic events. Immunosuppressive therapies, such as glucocorticoids and immunomodulatory agents, are commonly used to achieve disease re.. Read More»
DOI:
10.37421/2471-9544.2023.9.198
Journal of Vasculitis received 83 citations as per Google Scholar report