Department of Medical Oncology, Faculty of Medicine of Tunis, Salah Azaiez Institute, El Manar University, Tunis, Tunisia
Case Report
Non Metastatic Rhabdomyosarcoma in Children:
Therapeutic Outcome and Prognostic Factors of a Single
Institution Case Series
Author(s): Feryel Letaief Ksontini*, Dorra Tajina-Abdelmaksoud, Safia Yahiaoui, Azza Gabsi, Amina Mokrani and Amel Mezlini
Background: Rhabdomyosarcoma (RMS) is the most common soft tissue tumor in childhood with a cure rate of 70% in localized disease. We aimed to study the
prognostic factors of non-metastatic RMS in Tunisian paediatric patients.
Methods: We reviewed data of children aged <18 years, treated in the Salah Azaiez Institute for a localized RMS during 20 years. Prognostic factors were studied
and survival data analysed.
Results: 75 patients were included. Mean follow up was 30 months. The 5-year OS and DFS were 50% and 26%, respectively. By univariate analysis, DFS was
significantly correlated to chemotherapy, radiotherapy (RT) and post-surgical RT with p 0.02, 0.003 and 0.01, respectively. The surgery failed to be a significant factor.
We didn`t find any factor with a significant relationship with DFS in mu.. Read More»
Cancer Science & Therapy received 5332 citations as per Google Scholar report
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