Department of Biological Sciences, Franklin College of Arts and Sciences, University of Georgia, Athens, GA 30609, USA
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Endoplasmic Reticulum Stress and its Impact on Adipogenesis
Author(s): Andrea Lech*
The Endoplasmic Reticulum (ER) is a vital organelle responsible for protein folding, lipid synthesis, and calcium homeostasis within the cell. Under
conditions of cellular stress, such as nutrient overload or disturbances in calcium levels, the ER can become dysregulated, leading to a state known
as endoplasmic reticulum stress. ER stress has been implicated in various metabolic disorders, including obesity and type 2 diabetes. One key
aspect of metabolic regulation affected by ER stress is adipogenesis, the process by which precursor cells differentiate into adipocytes. This article
explores the mechanisms underlying ER stress, its role in adipogenesis, and its implications for metabolic health... Read More»
DOI:
10.37421/2168-9547.2024.13.416
Molecular Biology: Open Access received 607 citations as per Google Scholar report