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Immunochemistry & Immunopathology

ISSN: 2469-9756

Open Access

Aref MI

Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Egypt

Publications
  • Research Article   
    Immunomodulatory Role of Treg Lymphocytes in Chronic Hepatitis C Patients
    Author(s): Aref MI*

    Background: Regulatory T cells (Tregs) have a fundamental job in keeping up a harmony between forestalling immunopathology and enabling the insusceptible reaction to clear infections, in HCV infection, elevation of Tregs may cause insistent HCV infection. Objective: The current work aimed to clarify the immunomodulatory role of CD4+ CD25+ Foxp3+ Tregs in chronic hepatitis C (CHC) patients. Subjects and methods: This study incorporated two groups: 50 patients with chronic HCV infection of different classes of Child-Pugh classification (Child A, B and C) and control group; 25 healthy subjects. All patients were exposed to full history taking and finish clinical examination, as well as routine lab analysis including CBC, AST, ALT, ALP, GGT, PT, INR, blood urea, serum creatinine, ANA. HCV-Abs was me.. Read More»

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