RV College of Engineering, Bangalore, India
Review Article
A Pan Genome Review on Drug Resistance Mutations of Mycobacterium Tuberculosis; An Impending Threat to Healthcare
Author(s): Deepali VP, Shreeya SR, Arjun M and Vidya Niranjan*
Tuberculosis, a bacterial infection caused by the organism Mycobacterium Tuberculosis, is a widespread disease infecting roughly one-fourth of the world’s population. Although a majority of these cases remain asymptomatic, tuberculosis continues to be the second- most common cause of death by infectious disease worldwide. A growing problem that is being exacerbated by the excessive use of multiple types of antibiotics is the emergence of drug resistant strains of tuberculosis. The number of Multiple Drug-Resistant Tuberculosis (MDR-TB) and Extensively Drug Resistant Tuberculosis (XDR-TB) strains are steadily increasing, rendering conventional treatment options ineffective. In order to circumvent the issue of drug-resistance, it is imperative that we understand both the mechanisms involved in resistance and the genetic mutations that cause it. In this review we delve int.. Read More»
DOI:
10.37421/2684-4559.2020.4.131
Clinical Infectious Diseases: Open Access received 49 citations as per Google Scholar report