Department of Chemistry and Biochemistry, University of California, San Diego, CA 92093, USA
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Deciphering the Interplay of Multidrug Resistance Protein (MRP) with Drug Substrates: Insights into Pharmacokinetics and Therapeutic Strategies
Author(s): Arlet Georgina*
Multidrug resistance proteins (MRPs) constitute a family of membrane-bound transporters that play a pivotal role in cellular detoxification and the
disposition of endogenous and exogenous compounds. Their involvement in the efflux of various therapeutic agents has profound implications for
pharmacokinetics, drug efficacy, and resistance development. This article aims to elucidate the intricate interplay between MRPs and their drug
substrates, exploring the mechanisms underlying drug resistance and providing insights into potential therapeutic strategies... Read More»
DOI:
10.37421/2472-1042.2024.9.214
Pharmacoeconomics: Open Access received 95 citations as per Google Scholar report