Journal of Formulation Science & Bioavailability

Department of Orthopaedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany

Publications

• Mini Review   
  Navigating Formulation Challenges: Innovations in Bioavailability Evaluation
  Author(s): Arno Kwade*
  
  Formulation challenges are ubiquitous in the pharmaceutical industry, often posing significant hurdles in the development of effective drug delivery systems. Among these challenges, optimizing bioavailability stands out as a paramount objective. Bioavailability, the fraction of administered drug that reaches systemic circulation, profoundly influences a drug's therapeutic efficacy and clinical outcomes. In this article, we explore the evolving landscape of bioavailability evaluation and the innovative strategies revolutionizing drug formulation to overcome these challenges. Bioavailability is a multifaceted concept influenced by various factors such as drug solubility, permeability, metabolism, and formulation characteristics. It is a critical determinant of a drug's pharmacokinetic profile, influencing its onset of action, duration of effect, and overall therapeut.. Read More»
  DOI: 10.37421/2577-0543.2024.8.191

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